Taub Institute: Genomics Core
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TaubCONNECT Research Perspectives:
2019 Archive

December 2019:

Activity-Dependent Nucleation of Dynamic Microtubules at Presynaptic Boutons Controls Neurotransmission

Role of Tau Protein in Remodeling of Circadian Neuronal Circuits and Sleep

Sleep Fragmentation, Microglial Aging, and Cognitive Impairment in Adults with and Without Alzheimer's Dementia

November 2019:

First Place: Studying Biochemical Mechanisms of Protective Gene Variants in Isogenic Stem Cell-derived Early Onset Alzheimerā€™s Disease Models

First Place: Glial Heterogeneity in Normal Human Cortex and Huntington Disease Interrogated Through Single Cell Nuclear RNA Sequencing

October 2019:

Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body

Promotion of Axon Growth by the Secreted End of a Transcription Factor

September 2019:

Increased Diameters of the Internal Cerebral Veins and the Basal Veins of Rosenthal Are Associated with White Matter Hyperintensity Volume

Synaptic and Memory Dysfunction Induced by Tau Oligomers is Rescued by up-regulation of the Nitric Oxide Cascade

Medicaid Contributes Substantial Costs to Dementia Care in an Ethnically Diverse Community Population

August 2019:

Neuroinflammation in Frontotemporal Lobar Degeneration Revealed by 11Cā€PBR28 PET

Live Imaging of ESCRT Proteins in Microfluidically Isolated Hippocampal Axons

July 2019:

Alzheimer's Association International Conference (AAIC 2019)

June 2019:

CpGā€Related SNPs in the MS4A Region Have a Doseā€Dependent Effect on Risk of Lateā€“Onset Alzheimer Disease

MFN2 Mutations in Charcotā€“Marieā€“Tooth Disease Alter Mitochondria-Associated ER Membrane Function but Do Not Impair Bioenergetics

May 2019:

Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease

Brain Biomarkers and Cognition Across Adulthood

April 2019:

Predicting Cognitive Improvement in Normal Pressure Hydrocephalus Patients Using Preoperative Neuropsychological Testing and Cerebrospinal Fluid Biomarkers

Brain Arterial Dilatation and the Risk of Alzheimer's Disease

March 2019:

Elevated Cellular Cholesterol in Familial Alzheimer's Presenilin 1 Mutation is Associated with Lipid Raft Localization of Ī²-Amyloid Precursor Protein

FDG-PET Patterns Associated with Underlying Pathology in Corticobasal Syndrome

February 2019:

Effect of Aerobic Exercise on Cognition in Younger Adults: A Randomized Clinical Trial

Exercise-linked FNDC5/Irisin Rescues Synaptic Plasticity and Memory Defects in Alzheimerā€™s Models

January 2019:

A Tau Homeostasis Signature Is Linked with the Cellular and Regional Vulnerability of Excitatory Neurons to Tau Pathology

Between-network Functional Connectivity Is Modified by Age and Cognitive Task Domain

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