Taub Institute: Genomics Core
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TaubCONNECT Research Perspectives:
2018 Archive

December 2018:

Epigenome-Wide Study Uncovers Large-Scale Changes in Histone Acetylation Driven by Tau Pathology in Aging and Alzheimer’s Human Brains

Semantic Network Function Captured by Word Frequency in Nondemented APOE ε4 Carriers

November 2018:

First Place: NSUN2 is Dysregulated in Alzheimer's Disease

First Place: High-throughput Disease Modeling to Uncover Shared and Unique Characteristics Among Neurodegenerative Diseases

October 2018:

Homeostatic Plasticity Scales Dendritic Spine Volumes and Changes the Threshold and Specificity of Hebbian Plasticity

An MRI Measure of Degenerative and Cerebrovascular Pathology in Alzheimer Disease

Integrative Transcriptome Analyses of the Aging Brain Implicate Altered Splicing in Alzheimer's Disease Susceptibility

September 2018:

Clinical Experience with Cerebrospinal Fluid Aβ42, Total and Phosphorylated Tau in the Evaluation of 1,016 Individuals for Suspected Dementia

Evaluation of TDP-43 Proteinopathy and Hippocampal Sclerosis in Relation to APOE ε4 Haplotype Status: A Community-Based Cohort Study

August 2018:

A Multi-Omic Atlas of the Human Frontal Cortex for Aging and Alzheimer's Disease Research

An Alzheimer's Linked Loss-of-Function CLN5 Variant Impairs Cathepsin D Maturation Consistent with a Retromer Trafficking Defect

Letter and Category Fluency Performance Correlates with Distinct Patterns of Cortical Thickness in Older Adults

July 2018:

Activating Transcription Factor 4 (ATF4) Regulates Neuronal Activity by Controlling GABABR Trafficking

Whole-exome Sequencing in 20,197 Persons for Rare Variants in Alzheimer's Disease

June 2018:

Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease

Preparation of Tau Oligomers After the Protein Extraction from Bacteria and Brain Cortices

May 2018:

Whole Genome Sequencing in Caribbean Hispanic Families Associated with Late-Onset Alzheimer's Disease (LOAD)

Oligomeric Aβ1-42 Triggers the Generation of a Retrograde Signaling Complex from Sentinel mRNAs in Axons

April 2018:

Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein

Medical Retirement from Sport after Concussions: A Practical Guide for a Difficult Discussion

March 2018:

Cross Domain Self-Monitoring in Anosognosia for Memory Loss in Alzheimer's Disease

White Matter Changes in Alzheimer's Disease: A Focus on Myelin and Oligodendrocytes

February 2018:

ZCCHC17 is a Master Regulator of Synaptic Gene Expression in Alzheimer's Disease

Imaging Translocator Protein as a Biomarker of Neuroinflammation in Dementia

A Transcriptomic Atlas of Aged Human Microglia

January 2018:

Neuronal Lysosomal Dysfunction Releases Exosomes Harboring APP C-terminal Fragments and Unique Lipid Signatures

An Inflammation-Related Nutrient Pattern is Associated with Both Brain and Cognitive Measures in a Multiethnic Elderly Population

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