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Richard Mayeux, MD, MSc

Chairman & Neurologist-in-Chief, Department of Neurology
Gertrude H. Sergievsky Professor of Neurology, Psychiatry, and Epidemiology
Director, Gertrude H. Sergievsky Center
Co-Director, Taub Institute for Research on Alzheimer's Disease and the Aging Brain

Richard Mayeux, MD, MSc
Phone: 212-305-2391
Fax: 212-305-2518
Email: rpm2@cumc.columbia.edu

Richard Mayeux is the Gertrude H. Sergievsky Professor of Neurology, Psychiatry, and Epidemiology at Columbia University. He is the director of the Gertrude H. Sergievsky Center and the co-director of the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Chairman Department of Neurology and Neurologist-in-Chief at New York Presbyterian Hospital. Born in New Orleans, Louisiana, he is a graduate of Oklahoma State University and the University of Oklahoma Health Sciences, School of Medicine. He also holds a masters degree in Epidemiology from Columbia University. He completed residencies in both Internal Medicine (Boston City Hospital, Boston University) and Neurology (Columbia Presbyterian Medical Center, Columbia College of Physicians and Surgeons). He also completed post-doctoral training fellowship in Behavioral Neurology at the Boston Veterans Administration Medical Center (at Boston University) with D. Frank Benson, funded by the National Institute of Health.

In 1992, Dr. Mayeux received the Leadership and Excellence in Alzheimer disease Award from the National Institute of Aging for his investigation of genetic and environmental interaction in the etiology and pathogenesis of Alzheimer disease and related forms of dementia. He has been elected to the Association of American Physicians, the American Epidemiological Society and The Institute of Medicine of the National Academies. He is also the 2007 recipient of the American Academy of Neurology's Potamkin Award for his research on Alzheimer's disease.

Research Interests

Since 1989, he has led a multidisciplinary, population-based, epidemiological investigation of Alzheimer disease and related conditions known as the Washington Heights-Inwood Community Aging Project. This body of work spanning a period of 18 years constitutes most of our current knowledge of the on the rates and risk factors for Alzheimer' disease among elderly from African-American and Caribbean Hispanic. This study has provided information on the relationship between Alzheimer disease and numerous risk factors; genotypic variability of apolipoprotein-e4 risk in different ethnic groups; and the relationship of alterations in lipid metabolism and risk of dementia.

He also directs a genetic linkage study of Alzheimer's disease in Caribbean Hispanic families. We have completed two full genome-wide scans in these families and are working to fine map regions of interest. We recently identified genetic variants in the sortilin-related receptor, SORL1 related to Alzheimer's disease.

Mayeux is the coordinating investigator for the National Institute on Aging - Late Onset Alzheimer's Disease Family Study. This study began in 2002 with the goal of identifying 1,000 families multiply affected by Alzheimer' disease.

Most recently, he is the lead investigator in a collaborative study of families that display exceptional survival and longevity.

Recent Publications

- RubMed.gov

The Gertrude H. Sergievsky Center
630 West 168 Street, New York, NY 10032
Phone: 212-305-2515
Fax: 212-305-2426

Copyright ©Gertrude H. Sergievsky Center, Columbia University Irving Medical Center
Last updated: December 19, 2019     |    COMMENTS: administrative email
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